Úvod Laboratorní plasty Zkumavky Microcentrifuge Tube 1.5 ml Microcentrifuge Tube SALSA MLPA P371 Microdeletion-5 probemix - 100 reactions

SALSA MLPA P371 Microdeletion-5 probemix - 100 reactions

application: Microdeletion follow-up

region: 2p16, Langer Giedion, 9q22, WAGR, 15q24, 17q21 Detailní informace

Cena s DPH € 1 147.08
Cena bez DPH € 948.00
 100 react
Dostupnost Skladem
Kód produktu P371-100R

Nejnovější informace o produktu naleznete exklusivně na stránkách výrobce MRC-Holland www.mlpa.com (nové okno)

Detailní popis SALSA MLPA P371 Microdeletion-5 probemix - 100 reactions

P371-025R SALSA MLPA P371 Microdeletion syndromes 5 probemix – 100 rxn

The purpose of the P371 probemix is to further investigate results found with the P245 Microdeletion probemix. The P245 probemix provides a possibility to screen samples for 21 different microdeletion syndromes in a single reaction. For confirmation of results obtained with this P245 kit, four different probemixes are now available with additional probes in these 21 regions: P371, P372, P373 and P374 Microdeletion syndromes.

This P371 probemix contains probes for the 2p16 microdeletion syndrome region (8 probes), the Langer Giedion region on 8q24 (10 probes), the 9q22 microdeletion syndrome region (5 probes), the WAGR syndrome region on 11p13 (7 probes), the 15q24 microdeletion syndrome region (9 probes) and the 17q21 microdeletion syndrome region (8 probes).

This SALSA® MLPA® kit is designed to detect deletions/duplications of one or more sequences in the aforementioned regions. Heterozygous deletions of recognition sequences should give a 35-50% reduced relative peak area of the amplification product of that probe. Note that a mutation or polymorphism in the sequence detected by a probe can also cause a reduction in relative peak area, even when not located exactly on the ligation site! In addition, some probe signals are more sensitive to sample purity and small changes in experimental conditions. Therefore, deletions and duplications detected by MLPA should always be confirmed by other methods. Not all deletions and duplications detected by MLPA will be pathogenic; users should always verify the latest scientific literature when interpreting their findings.

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